Email: hebowden@arcbio.com
Phone: (408) 840-3643
Phone: (408) 840-3643
In Vitro Toxicity Testing
Too many compounds are never brought to market because of inadequate testing, interdepartmental communication gaps, lack of guidance, and/or insufficient funds. Poorly designed toxicity studies often result in a rejected IND (Investigational New Drug) application. ARCBio seeks to help close the gap between research, development, clinical testing, and FDA approval by providing unparalleled in vitro toxicology services.
The purpose of drug delivery and discovery is to solve some of man's greatest and most difficult problems; ARCBio strives to play a key role in that success.
Great Results and Great Customer Service
ARCBio's goal is to make the drug/drug delivery compound screening process and preclinical trial period as efficient and painless as possible. We identify drug and drug delivery therapies that are worth pursuing by
- Using protocols that are approved internationally (FDA, OECD, NCI).
- Modifying protocols to meet your needs.
- Maintaining high standards and strictly adhering to GLP.
- Valuing your time and money.
- Providing excellent data in a format based on FDA-provided templates.
ARCBio follows these guidelines to ensure that the relationship between the toxicity lab and the chemistry lab is optimized to produce successful compounds.
General Design
First, ARCBio uses general screening assays and common cell lines to narrow down the compounds that are the most likely to succeed. We actively communicate our results with your chemists to tweak promising compounds to reach the LOAELS (Lowest Observed Adverse Effect Level). Then we execute a tailored testing platform that involves a variety of cell lines. These cell lines are selected based on the target effects of the compounds.
Cell Uptake
Cell uptake studies are critical to understanding toxicity data. ARCBio specializes in fluorescent microscopy.
Preclinical Studies
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