Resources

Evaluation of the Galileo™ Pathogen Solution Next-Generation Sequencing Pipeline for the Identification and Quantification of DNA Viruses in Transplant Patients
Solid organ and hematopoietic stem cell transplant recipients are uniquely susceptible to infections, often with increased severity, due to a number of common and opportunistic viruses. Next-generation sequencing (NGS) has the potential to enable clinicians to determine the presence and abundance of transplant-related viruses with unprecedented precision, as well as identify co-infections in an unbiased manner.
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Evaluation of a Next-Generation Sequencing Metagenomics Assay to Detect and Quantify DNA Viruses in Plasma from Transplant Patients
Viral infections are major causes of morbidity and mortality in solid organ and hematopoietic stem cell transplant patients. The Galileo Pathogen Solution RUO assay is a sample to result metagenomic pipeline designed to simultaneously detect and quantify 10 DNA viruses.
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Performance of an NGS-based Metagenomics Assay to Simultaneously Detect and Quantify Multiple DNA Viruses
Galileo Pathogen Solution is a sample to report mNGS pipeline for comprehensive pathogen detection that eliminates the need to
query specific pathogens independently. In this RUO beta study, we demonstrate the use of an mNGS pipeline using Arc Bio Galileo
Pathogen Solution (GPS) for identification of DNA viruses in residual EDTA plasma specimens by comparing with standard of care qPCR assays.
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Megaplasmids on the Rise: Combining Sequencing Approaches to Fully Resolve a Carbapenemase – Encoding Plasmid in a Novel Pseudomonas Species
Horizontal transfer of plasmids plays a pivotal role in the dissemination of antibiotic resistance genes and emergence of multidrug-resistant bacteria. Here, we combined Nanopore and Illumina sequencing to fully assemble a carbapenemase-encoding megaplasmid carried by an isolate belonging to a putative novel Pseudomonas species.
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